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Moving Beyond Simple Wear Reduction  - E1 Antioxidant Infused Technology, the first vitamin E stabilized highly crosslinked polyethylene bearing material, is unlike any other polyethylene currently available for joint replacement. 

Biomet's E1 Antioxidant Infused Technology is a second generation material that has been shown in testing to provide high mechanical strength and oxidative stability.1

E1 Antioxidant Infused Technology can provide an optimal combination of acetabular fixation and low wear1 when used with the Regenerex™ RingLoc®+ Modular Shell.

The liners are available in 28mm, 32mm and 36mm inner diameters.

The key benefits of E1 Antioxidant Infused Technology include:

  • Higher levels of crosslinking for better wear performance
  • Greater strength than first generation remelted HXLPE1-3 
  • True oxidative protection without remelting1

The E1™ Antioxidant Infused Technology Process

Surpassing the limitations of first generation highly crosslinked polyethylene, E1 Antioxidant Infused Technology is truly a unique technology developed by Biomet's engineers and the research power of Massachusetts General Hospital.

  • Produced using a patent pending second-generation technology and proprietary process.
  • Isostatically compression molded polyethylene barstock, as used in clinically proven ArCom® polyethylene, is processed below the melt temperature to maintain the strength of the crosslinked polyethylene.
  • Infused with vitamin E to stabilize free radicals and prevent oxidative degradation.

Testing has shown that E1 Antioxidant Infused Technology offers: E1

  • Ultra-low wear rates with large heads: 95 percent wear reduction when comparing 40mm E1™ liners to 36mm ArCom® liners and 99 percent wear reduction with smaller femoral heads when compared to already low ArComXL® polyethylene.1
  • Fatigue strength greater than first generation re-melted HXLPE.1-3
  • Stronger than sequentially crosslinked and annealed materials after an environmental stress cracking (ESC) study.1

True oxidative protection without re-melting: no evidence of measurable oxidation.1 


1Halley, D. et al. Recurrent Dislocation After Total Hip Replacement with a Large Prosthetic Femoral Head. Journal of Bone and Joint Surgery. 86-A(4): 827– 30, 2004.
2Bhattacharyya, S. et al. Severe In Vivo Oxidation in a Limited Series of Retrieved Highly-Crosslinked UHMWPE Acetabular Components with Residual Free Radicals. Paper No. 0276. ORS San Francisco, CA. March 2004.
3Currier, B.H. et al. Crossfire Retrievals—What Can We Learn? Paper No. 1182. ORS. Washington D.C. March 2005.
4Ries, Michael D. Effect of Cross-linking on the Microstructure and Mechanical Properties of Ultra-high Molecular Weight Polyethylene. Clinical Orthopaedics and Related Research. (440):149–156, 2005.
5Biomet Biomaterials Laboratory ‘The revolutionary second generation vitamin E stabilsed highlycrosslinked UHMWPE’ Jan 2007
6Wannomnnomae, K. Environmental Stress Cracking of Two-Tocopherol Doped, Irradiated UHMWPEs and Two Contemporary UHMWPEs. Report Provided by the Orthopaedic Biomechanics and Biomaterials Laboratory at Massachusetts General Hospital. January 12, 2007.
7Bhambri, S. et al. The effect of aging on mechanical properties of melt-annealed highly crosslinked UHMWPE. Crosslinked and Thermally Treated Ultra-High Molecular Weight Polyethylene for Joint Replacements. 171–82, 2004.
8Muratoglu, O. et al. Wear Resistance and Mechanical Properties of Highly Cross-Linked, Ultrahigh-Molecular Weight Polyethylene Doped With Vitamin E. The Journal of Arthroplasty. 21(4): 580–591, 2006